Mark the letter A, B, C or D on your answer sheet to indicate the best arrangement of utterances or sentences to make a meaningful exchange or text in each of the following questions from 13 to 17.

1. Another issue is that it weakens the immune system, making the body more susceptible to illnesses.
2. Staying up late can have numerous negative effects on both physical and mental health.
3. In conclusion, while occasional late nights may seem harmless, consistently staying up late can significantly harm overall well-being.
4. It can also negatively affect mood, increasing stress and irritability over time.
5. One major consequence is the disruption of the body’s natural sleep cycle, leading to fatigue and poor concentration during the day